Table 2.
Clinical and demographic data of IIM patients who had flare after second dose of vaccination against COVID-19, including age, gender type of vaccination, diagnosis, number of organs involved, treatment at the time of vaccination, severity of flare, type of flare, change in medication and outcome
| Parameters | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 |
|---|---|---|---|---|---|---|---|
| Age (years) | 28 | 42 | 47 | 55 | 68 | 52 | 51 |
| Gender (M/F) | F | F | F | F | F | M | M |
| Type of Vaccination | Moderna | Comirnaty | Comirnaty | Comirnaty | Comirnaty | Comirnaty | Comirnaty |
| Diagnosis | PM | ASS | ASS | DM | PM | PM | DM |
| Number of organs involved | Muscle | Skin and joint | Muscle | Muscle, skin, lung and GI | Muscle, skin, lung, heart and GI | Muscle and lung | Muscle and skin |
| Treatment at the time of vaccination | IVIG | GCs, MTX, RTX | MTX | GCs and MTX | MMF | RTX, Tacrolimus and GCs | GCs and MTX |
| Severity of flare | Mild | Mild | Major | Mild | Mild | Life-threatening | Mild |
| Type of flare | Muscle | Muscle | Muscle, heart and GI | Skin | Muscle | Macrophage activation syndrome | Muscle |
| Change in medication | No | Yes | Yes | Yes | No | Yes | No |
| Outcome | Resolved | Resolved | Resolved | Resolved | Resolved | Death | Resolved |