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. 2022 Jun 24;13(5):1149–1157. doi: 10.1007/s41999-022-00668-8

Table 2.

Unadjusted and Adjusted time ratios for all-cause mortality in hospitalised individuals with or without COVID-19

Main effects Unadjusted
n = 103,561
Adjusted
n = 103,009
Time ratio 95% CI p-value Time ratio 95% CI p-value
U072 Reference Reference Reference Reference Reference Reference
U071 0.88 (0.78, 0.98)  < 0.001 0.84 (0.76, 0.93) 0.001
Low HFRS Reference Reference Reference Reference Reference Reference
Intermediate HFRS 0.82 (0.78, 0.85)  < 0.001 0.85 (0.81, 0.89)  < 0.001
High HFRS 0.90 (0.86, 0.94) 0.003 0.99 (0.95, 1.04) 0.704
Interaction effects
 Low HFRS* U071 Reference Reference Reference Reference Reference Reference
 Intermediate HFRS* U071 0.86 (0.76, 0.99) 0.029 0.88 (0.78, 1.0) 0.048
 High HFRS* U071 0.79 (0.70, 0.90)  < 0.001 0.80 (0.71, 0.91)  < 0.001
Main effects for adjusted model
 Age (per year) 0.97 (0.97, 0.97)  < 0.001
 Male Reference Reference Reference
 Female 0.69 (0.67, 0.71)  < 0.001
 Charlson comorbidity Index = 0 Reference Reference Reference
 Charlson comorbidity Index = 1 0.72 (0.69, 0.76)  < 0.001
 Charlson comorbidity Index = 2 0.68 (0.65, 0.71)  < 0.001
 Charlson comorbidity Index = 3 +  0.58 (0.56, 0.61)  < 0.001
 Deprivation quintile 1 Reference Reference Reference
 Deprivation quintile 2 1.06 (1.02, 1.10) 0.006
 Deprivation quintile 3 1.04 (0.99, 1.08) 0.093
 Deprivation quintile 4 1.07 (1.03, 1.12) 0.001
 Deprivation quintile 5 1.15 (1.10, 1.20)  < 0.001
 White British Reference Reference Reference
 Asian 0.81 (0.74, 0.88)  < 0.001
 Afro-Caribbean 0.58 (0.55, 0.62)  < 0.001
 Other 0.83 (0.80, 0.87)  < 0.001
 Previous admission 1.0 (1.0, 1.0) 0.003
 Number of procedure 1.10 (1.10, 1.10)  < 0.001
 ACSC 1.18 (1.13, 1.23)  < 0.001

Reference categories, U072, Low HFRS, Low HFRS* U072, male, deprivation quintile 1, Charlson Comorbidity Index = 0, Previous admissions = 0 and White British