Table 2.
Biochemical markers and lipid profile levels of patients with mild and severe COVID-19
| Parameters | Normal range | Mild group (n = 54) | Severe group (n = 58) | p value |
|---|---|---|---|---|
| d-Dimer (UgFEU/mL), median (IQR) | Less than 0.50 | 0.65 (0.2–0.72) | 0.50 (0.25–1.0) | 0.03* |
| Lactate dehydrogenase (LDH) (U/L), median (IQR) | 140–280 | 265.5 (220.5–407.2) | 509.0 (344–610) | 0.001* |
| Ferritin (ng/mL), median (IQR) | 20–300 | 311.0 (171.5–582) | 432.5 (286.7–980.2) | 0.014* |
| C-reactive protein (IU/mL), median (IQR) | Less than 10.0 | 58.5 (10.3–99.2) | 97.3 (33.2–164.2) | 0.006 |
| Serum creatinine (mg/dL), median (IQR) | 0.6–1.2 | 1.2 (1.0–1.5) | 1.0 (1.0–1.5) | 0.10 |
| WBCs (×103/µL), median (IQR) | 4.0–11.0 | 6.25 (4.5–8.8) | 8.3 (5.2–12.1) | 0.005* |
| Total cholesterol (mg/dL), mean ± SD | 200–240 | 193.6 ± 47.3 | 197.3 ± 62.1 | 0.759 |
| Triacylglycerols (mg/dL), mean ± SD | Up to 150 | 176.5 ± 87.5 | 192.0 ± 53.5 | 0.036* |
| LDL-C (mg/dL), mean ± SD | Up to 100 | 105.7 ± 39.7 | 90.7 ± 33.6 | 0.193 |
| HDL-C (mg/dL), mean ± SD | Up to 30 | 38.6 ± 12.8 | 41.0 ± 12.7 | 0.559 |
HDL-C high-density lipoprotein cholesterol, IQR interquartile range, LDL-C low-density lipoprotein cholesterol, SD standard deviation, WBC white blood cell count
*p value < 0.05 was accepted as statistically significant