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. 2022 Jun 15;24(6):e36004. doi: 10.2196/36004

Table 2.

Cochrane risk-of-bias tool version 2 summary.

Study, year Randomization process Deviations from intended interventions Missing outcome data Measurement of the outcome Selection of the reported result Overall
Effectiveness outcome assessments

An et al, 2013 [18] Low Some concerns High Some concerns High High

Arjadi et al, 2018 [19] Low Low Low Low Low Low


Day et al, 2013 [20] Low Low Low Low Some concerns Some concerns

Dirkse et al, 2020 [21] Low Low Low Low Some concerns Some concerns

Farrer et al, 2011 [22] Some concerns Low Low Low High High

Flynn et al, 2020 [23] Low High High Low Some concerns High

Heber et al, 2016 [24] Low Low Low Low Some concerns Some concerns

Kobak et al, 2015 [25] Some concerns High Low Low Some concerns High

Possemato et al, 2019 [26] Low Low Low Some concerns Some concerns Some concerns

Robinson et al, 2010 [28] Some concerns Low Low Some concerns Low Some concerns

Rosso et al, 2017 [29] Low Low Low Low Some concerns Some concerns

Titov et al, 2010 [30] Some concerns Low High Low Some concerns High
Adherence outcome assessments—completion of whole intervention

Day et al, 2013 [20] Low Low Low Low Low Low

Dirkse et al, 2020 [21] Some concerns Low Low Low Low Some concerns

Farrer et al, 2011 [22] Some concerns Low Low Low Low Some concerns

Flynn et al, 2020 [23] Low High Low Low Low High

Heber et al, 2016 [24] Low Some concerns Low Low Low Some
Concerns

Proudfoot et al, 2012 [27] Low Low Low Low High High

Robinson et al, 2010 [28] Some concerns Low Low Low Low Some concerns

Rosso et al, 2017 [29] Low Low Low Low Low Low

Titov et al, 2010 [30] Some concerns Low Low Low Low Some concerns
Adherence outcome assessments—completion of minimum dose

An et al, 2013 [18] Low Some concerns Low Low Low Some concerns

Farrer et al, 2011 [22] Some concerns Low Low Low Low Some concerns

Proudfoot et al, 2012 [27] Low Low Low Low High High
Adherence outcome assessments—percentage completion of each intervention module

Arjadi et al, 2018 [19] Low Low Low Low Low Low

Farrer et al, 2011 [22] Some concerns Low Low Low Low Some concerns
Adherence outcome assessments—mean number of modules completed

Possemato et al, 2019 [26] Low Low Low Low Some concerns Some concerns
Process outcome assessments

Day et al, 2013 [20] Low Low High High Low High

Dirkse et al, 2020 [21] Low Low Low High Some concerns High

Heber et al, 2016 [24] Low Some concerns High Low Low High

Kobak et al, 2015 [25] Some concerns High Low Some concerns Some concerns High

Possemato et al, 2019 [26] Low Low High High Low High

Robinson et al, 2010 [28] Some concerns Low High Low Low High

Titov et al, 2010 [30] Some concerns Low High High Some concerns High