Table 3.
Clinical characteristics and blood biochemical features in PWPs and HCs.
| PD-01 | PD-02 | PD-03 | PD-04 | PD-05 | PD-06 | HC-01 | HC-02 | HC-03 | HC-04 | HC-05 | HC-06 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sex (male/female) | Fmale | Male | Fmale | Fmale | Male | Fmale | Fmale | Male | Fmale | Male | Fmale | Fmale |
| Age (y) | 67 | 55 | 68 | 62 | 52 | 66 | 65 | 52 | 67 | 55 | 62 | 64 |
| Duration (y) | 8 | 8 | 9 | 7 | 9 | 2 | – | – | – | – | – | – |
| H and Y (score) | 2.5 | 2 | 2.5 | 2 | 1.5 | 2 | – | – | – | – | – | – |
| UPDRS III-off (score) | 48 | 31 | 53 | 28 | 25 | 18 | – | – | – | – | – | – |
| SBP (mmHg) | 91 | 155 | 117 | 125 | 117 | 127 | – | – | – | – | – | – |
| DBP (mmHg) | 61 | 91 | 79 | 70 | 73 | 57 | – | – | – | – | – | – |
| RBC (1012/L) | 4.7 | 4.92 | 4.39 | 4.48 | 4.74 | 4.32 | – | – | – | – | – | – |
| Hb (g/L) | 140 | 153 | 127 | 135 | 154 | 130 | – | – | – | – | – | – |
| WBC (109/L) | 6.85 | 6.45 | 5.67 | 7.44 | 4.6 | 7.68 | – | – | – | – | – | – |
| NC (1049/L) | 55.6 | 4.34 | 3.16 | 5.01 | 2.54 | 4.66 | – | – | – | – | – | – |
| NR (%) | 3.8 | 67.2 | 55.7 | 67.5 | 55.3 | 60.6 | – | – | – | – | – | – |
| Plt (109/L) | 191 | 231 | 240 | 242 | 226 | 223 | – | – | – | – | – | – |
| Na (mmol/L) | 145 | 140 | 141 | 141 | 143 | 145 | – | – | – | – | – | – |
| K (mmol/L) | 4.2 | 3.8 | 3.7 | 4.1 | 4 | 4.1 | – | – | – | – | – | – |
| Ca (mmol/L) | 2.36 | 2.54 | 2.47 | 2.24 | 2.32 | 2.35 | – | – | – | – | – | – |
| ALT (U/L) | 12 | 20 | 26 | 15 | 24 | 9 | – | – | – | – | – | – |
| AST (U/L) | 18 | 16 | 19 | 18 | 22 | 17 | – | – | – | – | – | – |
| TBIL (umol/L) | 15.1 | 19.8 | 15.9 | 11.6 | 9.5 | 14.5 | – | – | – | – | – | – |
| GHb (%) | 6.6 | 7.1 | 6.6 | 5.9 | 5.4 | 5.8 | – | – | – | – | – | – |
| Cre (umol/L) | 64.8 | 62.2 | 61 | 60.1 | 80.3 | 72.6 | – | – | – | – | – | – |
| BUN (mmol/L) | 5.7 | 4.3 | 6.1 | 4.5 | 4.1 | 5.1 | – | – | – | – | – | – |
PWPs, patients with PD; HCs, Healthy controls; H and Y, HoehnandYahr; UPDRS, Unified Parkinson Disease Rating Scale; SBP, systolic blood pressure; DBP, diastolic blood pressure; RBC, red blood cell count; Hb, hemoglobin; WBC, white blood cell count; NC, neutrophil count; NR, neutrophil ratio; Plt, platelet; Na, sodium ion; K, potassium ion; Ca, calcium ion; ALT, alanine transaminase; AST, aspartate aminotransferase; TBIL, total bilirubin; GHb, glycated hemoglobin; Cre, creatinine; BUN, blood urea nitrogen.