Table 4.
Eicosapentaenoic (EPA) metabolites biosynthesis.
| RvE1 | RvE2 | RvE3 | 18-HEPE | |
|---|---|---|---|---|
| Non-CF | 3.14 ± 0.55 | 6.98 ± 3.45 | 0.00 ± 0.04 | 6.18 ± 5.50 |
| CF | 2.78 ± 0.52 | 6.79 ± 3.65 | -0.09 ± 0.04 | -0.94 ± 0.63 |
| non-CF vs CF | NS | NS | 0.04 | NS |
| F non-CF | 2.92 ± 0.72 | 8.68 ± 5.40 | -0.02 ± 0.06 | 1.38 ± 2.72 |
| M non-CF | 3.49 ± 0.65 | 4.15 ± 2.23 | 0.05 ± 0.06 | 17.18 ± 16.93 |
| F CF | 1.28 ± 0.55 | 8.68 ± 7.031 | -0.13 ± 0.04 | -0.83 ± 0.32 |
| M CF | 4.10 ± 1.90 | 4.90 ± 2.63 | -0.06 ± 0.08 | -1.06 ± 1.27 |
| F CF vs M CF | NS | NS | NS | NS |
| F non-CF vs M non-CF | NS | NS | NS | NS |
| F non-CF vs F CF | NS | NS | NS | NS |
| M non-CF vs M CF | NS | NS | 0.05 | 0.09 |
Mean levels of each DHA metabolite (RvE1, RvE2, RvE3 and 18-HEPE) in non-CF and CF samples and in the subgroups of female and male subjects. Bold values are related to significant differences. NS, not significant.