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. 2022 Jun 14;48(2):139. doi: 10.3892/or.2022.8350

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effects of FANCI knockdown on NSCLC cell viability. (A) sh-FANCI silenced the expression of FANCI. FANCI silencing (B) inhibited A549 and H1299 cell proliferation, (C) promoted cell apoptosis (as revealed by flow cytometry), (D) upregulated Bax expression and downregulated Bcl-2 expression and (E) blocked the cell cycle in A549 and H1299 cells. *P<0.05, ***P<0.001. FANCI, Fanconi anemia complementation group I; NSCLC, non-small cell lung cancer; sh, short hairpin; NC, negative control.