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. 2022 Jun 14;48(2):139. doi: 10.3892/or.2022.8350

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Effect of FANCI knockdown on tumor growth in vivo. (A and B) Tumor weights and (C) volumes significantly decreased in the sh-FANCI group compared with those in the sh-NC group. (D) WB and (E) IHC results in tumor tissues showed that FANCI expression was significantly reduced in the sh-FANCI group. IHC revealed (F) decreased expression of Ki-67 and (G) increased expression of cleaved-caspase-3 in the sh-FANCI group. *P<0.05. FANCI, Fanconi anemia complementation group I; sh, short haisrpin; WB, western blotting; IHC, immunohistochemistry; NC, negative control.