Table 4.
Genotype and allele frequencies in controls and patients
| Polymorphisms | Genotypes | p-value | Alleles | O.R (95% CI) | p-value | |||
|---|---|---|---|---|---|---|---|---|
|
SELE rs3917406 Controls (n = 111) Patients (n = 101) |
CC (%) 43 (38.7%) 29 (28.7%) |
CT (%) 48 (43.4%) 37 (36.6%) |
TT (%) 20 (18%) 35 (34.7%) |
0.02 |
C 134 (60.3%) 95 (47.0%) |
T 88 (39.7%) 107 (53.0%) |
0.58 (0.397, 0.857) | 0.006 |
|
SELE rs5355 Controls (n = 111) Patients (n = 101) |
CC (%) 87 (87.4%) 91 (90.15%) |
CT (%) 22 (19.8%) 9 (8.9%) |
TT (%) 2 (1.8%) 1 (1%) |
0.043 |
C 196 (88.2%) 191 (94.6%) |
T 26 (11.8%) 11 (5.4%) |
2.3 (1.11, 4.79) | 0.022 |
|
CETP rs5882 Controls (n = 100) Patients (n = 100) |
GG (%) 28 (28%) 40 (40%) |
GA (%) 52 (52%) 45 (45%) |
AA (%) 20 (20%) 15 (15%) |
0.195 |
G 108 (54%) 125 (62.5%) |
A 92 (46%) 75 (37.5%) |
1.4 (0.95, 2.12) | 0.085 |
|
CETP rs708272 Controls (n = 100) Patients (n = 100) |
GG (%) 36 (36%) 27 (27%) |
GA (%) 43 (43%) 55 (55%) |
AA (%) 21 (21%) 18 (18%) |
0.217 |
G 115 (57.5%) 109 (54.5%) |
A 85 (42.5%) 91 (45.5%) |
0.885 (0.596, 1.31) | 0.546 |
|
MIA3 rs17465637 Controls (n = 80) Patients (n = 80) |
AA (%) 61 (76.3%) 52 (65%) |
AC (%) 18 (22.5%) 24 (30%) |
CC (%) 1 (1.2%) 4 (5%) |
0.19 |
A 140 (87.5%) 128 (80%) |
C 20 (12.5%) 32 (20%) |
0.57 (0.31, 1.05) | 0.069 |
|
SMAD3 rs17228212 Controls (n = 80) Patients (n = 80) |
TT (%) 80 (100%) 80 (100%) |
TC (%) 0 (0%) 0 (0%) |
CC (%) 0 (0%) 0 (0%) |
N.S |
T 160 (100%) 160 (100%) |
C 0 (0%) 0 (0%) |
1 | N.S |