Table 1.

Summary of behavioral alterations in Fmr1^−/y-PV and Fmr1⁻.^/y-SOM mice compared to control

Phenotype	Test	Fmr1−/y-PV	Fmr1−/y-SOM
Motor function and learning	Rotarod		Not shown (no deficit)
Anxiety-like behavior	Elevated plus maze	Increased time in closed arms and decreased time in the center	–
ASD-like behavior	Marble burying	–	–
	Self-grooming	–	–
	Y Water Maze	Increased errors during training	–
	Sociability and social novelty	Deficit in social novelty behavior	–
Learning and memory	Novel object recognition	–	–
	Object location memory	–	Not done
	Morris water maze	–	–
	Threat conditioning	Increased freezing during tone presentation (CS testing and reconsolidation)	–