Table 2.
The comparison between SLE patients with and without sexual dysfunction concerning the demographic and clinic characteristics, and the different indices
| Variables | With sexual dysfunction (n = 101) | Without sexual dysfunction (n = 27) | t/F/x2 | P |
|---|---|---|---|---|
| Age (years) | 40.90 ± 13.50 | 36.37 ± 6.84 | 2.44 | 0.018* |
| BMI (kg/m2) | 23.14 ± 4.28 | 23.02 ± 3.69 | 0.13 | 0.896 |
| Marital status | 10.94 | 0.001** | ||
| Single/divorced/widowed | 30 (29.7) | 1 (3.7) | ||
| Married | 70 (70.3) | 26 (96.3) | ||
| Having child (yes) | 68 (67.3) | 24 (88.9) | 4.90 | 0.027* |
| Education | 0.01 | 0.973 | ||
| Primary and below | 20 (19.8) | 4 (14.8) | ||
| Secondary | 29 (28.7) | 9 (33.3) | ||
| Graduate and above | 52 (51.5) | 14 (51.9) | ||
| Employment status | 1.17 | 0.279 | ||
| Unemployed | 53 (52.5) | 11 (40.7) | ||
| Employed | 48 (47.5) | 16 (59.3) | ||
| Income/person/month | 0.78 | 0.379 | ||
| ≤ 1000 Yuan | 2 (2.0) | 0 (0) | ||
| 1000–3000 yuan | 23 (22.8) | 5 (18.5) | ||
| 3000–5000 yuan | 28 (27.7) | 7 (25.9) | ||
| ≥ 5000 yuan | 48 (47.5) | 15 (55.6) | ||
| Health insurance (yes) | 86 (85.1) | 23 (85.2) | 0.01 | 0.996 |
| Religious beliefs (yes) | 13 (12.9) | 4 (14.8) | 0.07 | 0.792 |
| History of hospitalization (yes) | 81 (80.2) | 20 (74.1) | 0.48 | 0.488 |
| History of family (yes) | 14 (13.9) | 1 (3.7) | 2.13 | 0.145 |
| Comorbid condition (yes) | 62 (61.4) | 12 (44.4) | 2.51 | 0.113 |
| Residence | 0.01 | 0.974 | ||
| Urban | 90 (89.1) | 24 (88.9) | ||
| Rural | 11 (10.9) | 3 (11.1) | ||
| SLE disease duration (years) | 6.39 ± 7.22 | 3.80 ± 2.77 | 2.89 | 0.005** |
| VAS pain (range 0–10) | 2.00 ± 1.50 | 1.67 ± 1.14 | 1.07 | 0.286 |
| SLEDAI | 6.28 ± 7.88 | 2.78 ± 3.64 | 3.33 | 0.001** |
| DMARDs usage (yes) | 73 (72.3) | 26 (96.3) | 7.01 | 0.008** |
| Corticosteroid usage (yes) | 84 (83.2) | 23 (85.2) | 0.01 | 0.802 |
| Biologics usage (yes) | 18 (17.8) | 8 (29.6) | 1.84 | 0.176 |
| Depression (PHQ9) | 5.27 ± 4.88 | 2.81 ± 4.54 | 2.35 | 0.020* |
| Fatigue (MFI) | ||||
| General fatigue | 12.12 ± 3.09 | 10.67 ± 3.36 | 2.13 | 0.035* |
| Physical fatigue | 12.37 ± 3.53 | 10.67 ± 2.98 | 2.29 | 0.024* |
| Mental fatigue | 10.42 ± 3.67 | 8.12 ± 3.54 | 2.83 | 0.005** |
| Reduced motivation | 9.35 ± 2.87 | 8.56 ± 3.30 | 1.23 | 0.220 |
| Reduced activity | 11.67 ± 3.03 | 9.96 ± 4.00 | 2.01 | 0.046* |
| Total score | 56.43 ± 13.05 | 48.04 ± 13.51 | 2.95 | 0.004** |
| Quality of life (SF-12) | ||||
| PCS | 44.11 ± 8.85 | 47.48 ± 7.91 | − 1.80 | 0.075 |
| MCS | 45.96 ± 5.77 | 46.39 ± 4.82 | − 0.36 | 0.720 |
| Total score | 90.06 ± 9.29 | 93.87 ± 8.07 | − 1.94 | 0.046* |
Data are presented as mean ± SD or number (%)
SLE Systemic Lupus Erythematosus, BMI Body Mass Index, VAS Visual Analog Scale, SLEDAI Systemic Lupus Erythematosus Disease Activity Index, DMARDs Disease-Modifying Anti-rheumatic Drugs, PDD Perceived Devaluation-Discrimination, PHQ-9 Patient Health Questionnaire-9, MFI Multiple Fatigue Inventory, SF-12 Short Form 12 health survey, PCS physical components summary, MCS mental components summary
*P < 0.05; **P < 0.01