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. Author manuscript; available in PMC: 2022 Jun 30.
Published in final edited form as: Adv Mater. 2021 Feb 9;33(12):e2004172. doi: 10.1002/adma.202004172

Figure 3.

Figure 3.

A) Fabrication of topographical substrate. a) Nanoimprint lithography. b) Hybrid technique. B) RAW 264.7 macrophage morphology on topographical gratings at 48 h. a) Elongation in the direction of 2 μm PDMS gratings. b) Natural round shape on planar PDMS. c) Elongation in the direction of 2 μm PLA gratings. d) Macrophage morphology on the border of 2 μm PLA gratings and planar surface. e–g) Macrophage elongation on PCL gratings. h–j) Native round morphology on planar surfaces. A,B) Reproduced with permission.[91]