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. 2022 Jun 16;13:927443. doi: 10.3389/fimmu.2022.927443

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Copyright © 2022 Sun, Zhang, Zhao, Yang, Shi, Xu, Liu, Guan, Shi and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genetic stability and growth of pPG-612-CK6-G/L.casei 393. (A) Identification of samples taken at different times for 50 consecutive generations, line 1: first generation sap; line 2: the 5th generation sap; line 3: the 10th generation sap; line 4: the 15th generation sap; line 5: the 20th generation sap; line 6: the 25th generation sap; line 7: the 30th generation sap; line 8: the 35th generation sap; line 9: the 40th generation sap; line 10: the 45th generation sap; line 11: the 50th generation sap; line 12: blank control; M: DNA marker DL2000; (B) Growth curves of pPG-612-CK6-G/L.casei, pPG-612/L.casei and L.casei over 36 h.