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. 2022 Jun 16;13:927443. doi: 10.3389/fimmu.2022.927443

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Copyright © 2022 Sun, Zhang, Zhao, Yang, Shi, Xu, Liu, Guan, Shi and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The relative expression levels of cytokines in the liver, spleen, kidney, intestine, gill, and skin mucus on the 15th day after secondary immunization. (A) the relative expression of IL-1β; (B) the relative expression of IL-4; (C) the relative expression of IL-6; (D) the relative expression of IRF1; (E) the relative expression of IRF3; (F) the relative expression of IRF7; (G) the relative expression of IFN; (H) the relative expression of MX1; (I) the relative expression of TNF-α. Data are presented as mean ± SD and P values were calculated using one-way ANOVA and LSD post hoc tests. * represents p<0.05, ** represents p<0.01.