. Author manuscript; available in PMC: 2023 May 19.

Published in final edited form as: Eur Respir J. 2022 May 19;59(5):2100569. doi: 10.1183/13993003.00569-2021

Table 5.

Association of blood AWT score with lung function and exacerbations

	Beta or IRR	95% CI	Adjusted p value
FEV₁pp^*	−3.4	−5.44, −1.42	0.04
FEV₁/FVC^*	−0.03	−0.04, −0.02	<0.0001
ΔFEV₁(ml)^†	−53.5	−81.6, −25.4	<0.01
Exacerbation frequency^‡	1.7	1,24, 2.38	0.04

Abbreviations: IRR = incidence rate ratio, FEV₁pp = FEV₁ percent predicted, ΔFEV₁/ml= change in FEV₁(ml) between over 5 years, adj.p = adjusted p value using Holm-Bonferroni correction

Linear regression adjusted for age, sex, race, body mass index, smoking status, smoking history (PY), emphysema (%). COPD n= 1026, control n = 1367

^†

Linear regression adjusted for age, sex, race, body mass index, smoking status, smoking history (PY), baseline FEV1 percent predicted, emphysema (%). COPD n = 1024, control n = 1360

^‡

Acute respiratory disease defined by flare up of chest troubles requiring antibiotic and/or steroid treatment[41]. Negative binomial regression adjusted for age, sex, race, smoking status, baseline FEV1 percent predicted, history of previous exacerbation. COPD n= 937, control n= 1244