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Gene-by-Gene calculation of pN/pS over phylogenetic time. (A) Bar plot showing the number of genes currently displaying a pN/pS > 1 and a pN/pS < 1. (B) From the alignment, we inferred the current pN/pS; however, when mapping different mutations onto the phylogeny, we inferred how the pN and pS rates changed over time. (C) Five categories grouping studied genes according to their trajectories.
