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. 2022 Jun 23;119(26):e2121513119. doi: 10.1073/pnas.2121513119

Fig. 4.

Fig. 4.

Kudinoside A relaxed the KCl-evoked contraction of the airway but not of the aorta or jejunum smooth muscle. (A) KE-A (30 μM) relaxed the ASM contraction evoked by 10 μM MCh or 64 mM KCl. (B and C) KE-A did not relax the tension force of the aorta and jejunum smooth muscle evoked by agonists and KCl depolarization. (D) The depolarization-evoked contraction of ASM was significantly induced by atropine. (E) The depolarization-evoked aortic contraction was partially inhibited by atropine. (F) The depolarization-evoked contraction of jejunum smooth muscle was not relaxed by atropine. (G) Quantitation of the data in A–C. (H) Quantitation of the data in D–F. *P < 0.05, **P < 0.01, unpaired Student’s t test; ###P < 0.001, unpaired Student’s t test. NE: norepinephrine.