TABLE 2.

Effect of intervention on primary and secondary outcomes at endline.

	Regression coefficient B (95% CI)	ICC	Effect size (95% CI)	P-value
Primary outcomes (all child outcomes)
Cognitive composite score	6.17 (4.29, 8.06)	0.07	0.85 (0.59, 1.11)	0.001
Language composite score	5.81 (3.69, 7.94)	0.10	0.69 (0.43, 0.94)	0.001
Motor composite score	4.87 (2.91, 6.82)	0.03	0.52 (0.31, 0.73)	0.001
Approach	0.48 (0.32, 0.65)	0.01	0.53 (0.35, 0.71)	0.001
Positive emotional tone	0.29 (0.11, 0.46)	0.02	0.36 (0.14, 0.58)	0.001
Cooperativeness	0.35 (0.17, 0.54)	0.04	0.43 (0.20, 0.66)	0.001
Vocalization	0.52 (0.33, 0.71)	0.03	0.40 (0.26, 0.55)	0.001
Height for age z-score	–	0.06	−0.16 (−0.31, −0.01)	0.06
Weight for age z-score	–	0.05	0.04 (−0.08, 0.15)	0.52
Weight for height z-score	–	0.05	0.20 (0.04, 0.35)	0.06
Secondary outcomes (parenting outcomes)
Child-rearing knowledge	7.87 (7.00, 8.73)	–	1.27 (1.13, 1.41)	<0.001
Home stimulation	5.35 (4.14, 6.56)	–	0.77 (0.60, 0.94)	<0.001
Maternal depression	−1.39 (−2.54, −0.23)	–	−0.18 (−0.34, −0.03)	0.02

ICC, intracluster correlation coefficient. 1 = intervention, 0 = control. Analyses were adjusted for child age and sex, tester/interviewer, baseline score as fixed effects and community clinic as a random effect. Analyses for child development and behavior outcomes also included place of test, and a place of test x group interaction term as fixed effects. p values for all 10 primary outcomes have been corrected for with Holm’s stepdown procedure.