Table 2.
Clinical Outcomes in Patients With High or Low ABCD‐GENE‐Score
| Variable |
High (≥10) ABCD‐GENE score (n=613) |
Low (<10) ABCD‐GENE score (n=3270) |
HR (95% CI) | P value |
|---|---|---|---|---|
| Time to first event analysis | ||||
| All‐cause death, MI, or stroke | 31 (5.2%) | 84 (2.6%) | 2.04 (1.35–3.07) | <0.001 |
| Cardiovascular death, MI, stroke, definite or probable ST, or severe recurrent ischemia | 46 (7.7%) | 146 (4.6%) | 1.74 (1.25–2.43) | 0.001 |
| All‐cause death | 11 (1.8%) | 32 (1.0%) | 1.92 (0.97–3.79) | 0.060 |
| Major/minor bleeding | 12 (2.0%) | 33 (1.0%) | 2.04 (1.06, 3.94) | 0.033 |
| Recurrent events analysis | ||||
| All‐cause death, MI, or stroke | 38 (6.5%) | 90 (2.9%) | 2.32 (1.61–3.37) | <0.001 |
| Cardiovascular death, MI, stroke, definite or probable ST, or severe recurrent ischemia | 57 (9.7%) | 162 (5.1%) | 1.90 (1.43–2.52) | <0.001 |
Estimates are calculated by the Kaplan‒Meier method.
ABCD‐GENE indicates Age, Body Mass Index, Chronic Kidney Disease, Diabetes, and Genotyping; HR, hazard ratio; MI, myocardial infarction; and ST, stent thrombosis.