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Effect of WEML on the expression of the Wnt target genes. HFDP cells were treated with indicated concentrations of WEML for 36 h. Real-time reverse transcription-polymerase chain reaction was performed to analyze mRNA expression levels of the Wnt target genes (A) AXIN2, (B) NKD1, and (C) MYC. Results are expressed as mean ± standard deviation (n = 3). *p < 0.05, **p < 0.01. WEML, water extract of Mangifera indica leaves; AXIN2, axin-2; NKD1, naked cuticle homolog 1.
