Figure 7.
Schematic diagram of hair growth promotion according to activation of Wnt signaling pathway by WEML treatment. WEML treatment significantly reduced the expression levels of both DKK1 and SRD5A2 involved in Wnt signal suppression activity and DHT synthesis, respectively, in HFDP cells. In addition, it effectively up-regulated Wnt target genes and down-regulated DKK1 expression increased by DHT treatment.