FIGURE 8.

Effects of PSB06126, ENPP1-Inh-C and L-p-bromotetramisole (L-p-BT) on hydrolysis of eATP by soluble enzymes in LP. (A–D) eATP hydrolysis by soluble enzymes in the presence of vehicle (0.1% DMSO) or PSB06126 (10 µM), ENPP1-Inh-C (50 µM) or L-p-bromotetramisole (L-p-BT) (100 µM). Asterisks denote significant difference of eATP decrease in the presence of ENPP1-Inh-C from vehicle controls. *p < 0.05, **p < 0.01, ****p < 0.0001. Open circles denote significant difference of eATP decrease in the presence of PSB06126 and vehicle control (panel A). ^oP<0.05, ^ooP<0.01.