Skip to main content
. 2022 Jun 17;18(6):e1010250. doi: 10.1371/journal.pcbi.1010250

Fig 7. Pairwise interactions among all connections.

Fig 7

An interaction matrix resulting from the PCIA procedure in which warmer colors show greater synergy and cooler colors indicate functional overlap (left). We excluded the values within a range of ±2 SD above and beyond the mean and applied the “Sprague effect” condition to the thresholded matrix (middle). On the right-hand side, we plotted the interaction network in which the nodes represent connections in the actual network, and the edges are interactions among them. Arrows show paradoxical-lesion effects (i → j).