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. 2022 Jun 30;17(6):e0269404. doi: 10.1371/journal.pone.0269404

Fig 6. Pants interacts with Rtn4/Nogo in vitro and in vivo.

Fig 6

A) Immunocytochemical co-localization of Pants and Nogo-A in cultured PantsSOG-Y hippocampal neurons B) AMPA receptor clustering at synapses where Pants colocalizes with Nogo-A versus Pants-free synapses in the absence of stimulation. C) Correlation between Pants-Nogo-A co-localization and GluR1 AMPA receptor fluorescence in the membrane of spine ROIs in the absence of stimulation. D) AMPA receptor clustering at synapses where Pants colocalizes with Nogo-A versus Pants-free synapses immediately after KCl stimulation. E) Correlation between Pants-Nogo-A co-localization and GluR1 AMPA receptor fluorescence in the membrane of spine ROIs immediately after KCl stimulation. n = 3 samples, 40 ROIs each.