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. 2022 Jun 30;17(6):e0269998. doi: 10.1371/journal.pone.0269998

Table 3. Univariate and multivariate analyses of overall survival in breast cancer patients.

Parameters Univariate analysis Multivariate analysis
HR 95%CI P value HR 95%CI P value
Age 1.91 1.39–2.63 0 2.16 1.36–3.45 0.0013
Histological type 0.93 0.74–1.17 0.543
Molecular subtype 1.01 0.88–1.16 0.901
ER 0.85 0.71–1.02 0.074
PR 0.87 0.73–1.03 0.096
HER-2 1.29 1.05–1.57 0.013 1.12 0.90–1.40 0.297
Menopause status 1.16 0.94–1.43 0.165
Stage 1.64 1.40–1.91 0 2.20 1.67–2.91 0.0000
Margin status 1.42 1.11–1.81 0.005 1.03 0.74–1.43 0.8795
Lymph node status 1.10 0.93–1.30 0.274
CCBL2 2.12 1.53–2.93 0 2.18 1.37–3.47 0.0011

Abbreviations: HR Hazard Ratio, CI confidence interval, bold values of P < 0.05 indicate statistically significant correlations