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. 2022 Jun 16;9:893977. doi: 10.3389/fsurg.2022.893977

Figure 3.

Figure 3

Prognostic value of m7G risk signature in HCC. (A) Overall survival difference between the high- and low-m7G-risk groups based on the Kaplan–Meier method. (B) ROC curves of clinicopathological features and m7G risk scores for predicting OSR. (C) Time-dependent ROC curves of the m7G risk score for predicting OSR. (D) Univariate independent prognostic analysis. (E) Multivariate independent prognostic analysis. (F) DCA results. “Model A” is the traditional prognostic model composed of age, histological grade, and TNM staging (blue line). “Model B” is the traditional prognostic model composed of age, histological grade, and clinical stage (red line). “Model C” is the improved model A with the m7G risk score (green line). “Model D” is the improved model B with the m7G risk score (light blue line). (G–H) Improvements brought by the m7G risk score in the predictive accuracy of TNM staging and clinical stage. OSR, overall survival rate; HR, hazards ratio; AUC, area under curve; TPR, true-positive rate; FPR, false-positive rate.