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. 2022 Feb 16;41(3):103–111. doi: 10.12938/bmfh.2021-081

Table 4. Microbial diversity before and after synbiotic supplementation in the non-responders and responders.

Measured values Change


Baseline 24 weeks 24 weeks
Phylogenic diversity Non-responders 26.4 ± 5.3 25.3 ± 5.5 −1.0 ± 2.7
Responders 26.8 ± 7.2 27.0 ± 6.5 0.2 ± 3.4
Observed OTU Non-responders 220.7 ± 61.4 209.7 ± 65.8 −11.0 ± 45.7
Responders 225.8 ± 70.5 225.6 ± 61.6 0.9 ± 40.3
Shannon index Non-responders 6.12 ± 0.60 5.82 ± 0.62 −0.30 ± 0.39
Responders 6.06 ± 0.75 6.10 ± 0.66 0.06 ± 0.57*

Change is expressed as the difference between the value measured at 24 weeks and the baseline value. *p<0.05 vs. Non-responders. OTU: observed operational taxonomic unit.