Table 2. Baseline demographic characteristics.
| Group A IDDVT a N = 1,016 |
Group B PDVT ± DDVT b N = 2,305 |
Group C PE ± any DVT N = 2,451 |
Total N = 5,772 |
|
|---|---|---|---|---|
| Age, y; mean ± SD | 58.2 ± 17.5 [57.1–59.3] |
61.8 ± 17.0 [61.1–62.5] |
63.0 ± 16.5 [62.4–63.7] |
61.7 ± 17.0 YY |
| Age group, n (%) | ||||
| < 65 y | 603 (59.4) [56.3–62.4] |
1182 (51.3) [49.2–53.3] |
1190 (48.6) [46.6–50.6] |
2975 (51.5) YY |
| 65 to <75 y | 211 (20.8) [18.3–23.4] |
542 (23.5) [21.8–25.3] |
575 (23.5) [21.8–25.2] |
1,328 (23.0) |
| ≥75 y | 202 (19.9) [17.5–22.5] |
581 (25.2) [23.4–27.0] |
686 (28.0) [26.2–29.8] |
1,469 (25.5) YY |
| Male, c n (%) | 496 (48.8) [45.7–51.9] |
1,221 (53.0) [50.9–55.0] |
1,208 (49.3) [47.3–51.3] |
2,925 (50.7) |
| Ethnicity, n (%) | ||||
| White | 830 (81.7) [78.2–84.0] |
1,812 (78.6) [76.9–80.3] |
1,737 (70.9) [69.0–72.7] |
4,379 (75.9) Y |
| Asian | 102 (10.0) [8.3–12.1] |
202 (8.8) [7.6–10.0] |
330 (13.5) [12.1–14.9] |
634 (11.0) |
| Black or African American | 11 (1.1) [0.5–1.9] |
54 (2.3) [1.8–3.0] |
104 (4.2) [3.5–5.1] |
169 (2.9) Y |
| Unknown | 72 (7.1) [5.6–8.8] |
228 (9.9) [8.7–11.2] |
264 (10.8) [9.6–12.1] |
564 (9.9) Y |
| Other d | 1 (0.1) [0.00–0.05] |
9 (0.4) [0.2–0.7] |
16 (0.7) [0.4–1.1] |
26 (0.5) |
| CrCl, e mL/min, mean ± SD | 102.0 ± 43.0 [98.5–105.5] |
92.1 ± 42.8 [89.3–94.3] |
94.2 ± 47.2 [92.1–96.3] |
94.5 ± 45.1 YY |
| BMI, f kg/m 2 , mean ± SD | 27.9 ± 5.3 [27.5–28.3] |
28.0 ± 5.7 [27.7–28.3] |
28.4 ± 6.7 [28.1–28.7] |
28.2 ± 6.1 |
| Weight, g kg, mean ± SD | 80.6 ± 18.3 [79.4–81.8] |
80.6 ± 19.3 [80.0–81.5] |
81.8 ± 21.9 [80.9–82.7] |
81.1 ± 20.3 |
| Height, h cm, mean ± SD | 169.7 ± 10.0 [168.0–169.4] |
169.3 ± 9.9 [168.9–169.8] |
169.3 ± 10.5 [168.8–169.8] |
169.4 ± 10.2 |
| Prior VTE event, n (%) | 108 (10.6) [8.8–12.7] |
289 (12.5) [11.2–14.0] |
235 (9.6) [8.5–10.8] |
632 (10.9) |
| Smoking history, i n (%) | ||||
| Non-smoker | 501 (49.3) [46.2–52.4] |
1,081 (46.9) [44.8–49.0] |
1,193 (48.7) [46.7–50.7] |
2,775 (48.1) |
| Current smoker | 180 (17.7) [15.4–20.2] |
369 (16.0) [14.5–17.6] |
330 (13.5) [12.1–14.9] |
886 (15.2) Y |
| Ex-smoker | 103 (10.1) [8.4–12.2] |
297 (12.9) [11.4–14.3] |
411 (16.8) [15.3–18.3] |
811 (14.1) Y |
| Unknown | 232 (22.8) [20.3–25.5] |
558 (24.2) [22.5–26.0] |
516 (21.1) [19.5–22.7] |
1,306 (22.6) |
| Insurance status for medication, j n (%) | ||||
| Public insurance | 535 (52.7) [49.5–55.8] |
1,152 (50.0) [47.9–52.0] |
1,059 (43.2) [41.2–45.2] |
2,746 (47.6) Y |
| Private insurance | 41 (4.0) [2.9–5.4] |
119 (5.2) [4.3–6.1] |
164 (6.7) [5.7–7.8] |
324 (5.6) Y |
| Out-of-pocket | 87 (8.6) [6.9–10.5] |
206 (8.9) [7.8–10.2] |
102 (4.2) [3.4–5.0] |
395 (6.8) Y |
| Multiple types | 35 (3.4) [2.4–4.8] |
110 (4.8) [3.9–5.7] |
131 (5.3) [4.5–6.3] |
276 (4.8) |
| Employment status, k n (%) | ||||
| Retired | 275 (27.1) [24.4–29.9] |
833 (36.1) [34.2–38.1] |
802 (32.7) [30.9–34.6] |
1,910 (33.1) YY |
| Works full time | 306 (30.1) [27.3–33.0] |
534 (23.2) [21.5–24.9] |
509 (20.8) [19.2–22.4] |
1,349 (23.4) YY |
| Unemployed | 87 (8.6) [6.9–10.5] |
222 (9.6) [8.5–10.9] |
298 (12.2) [10.9–13.5] |
607 (10.5) Y |
| Disabled | 12 (1.2) [0.6–2.1] |
122 (5.3) [4.4–6.3] |
83 (3.4) [2.7–4.2] |
217 (3.8) YY |
| Self-employed | 27 (2.7) [1.3–3.8] |
42 (1.8) [1.3–2.5] |
54 (2.2) [1.7–2.9] |
123 (2.1) |
| Works part-time | 24 (2.4) [1.5–3.5] |
48 (2.1) [1.5–2.8] |
38 (1.6) [1.1–2.1] |
110 (1.9) |
| Other | 19 (1.9) [1.1–2.9] |
59 (2.6) [2.0–3.3] |
57 (2.3) [1.8–3.0] |
135 (2.3) |
| Unknown | 270 (26.6) [23.9–29.4] |
488 (21.2) [19.5–22.9] |
634 (25.9) [24.1–27.6] |
1,392 (24.1) |
Abbreviations: BMI, body mass index; CrCl, creatinine clearance; DDVT, distal DVT; DVT, deep vein thrombosis; IDDVT, isolated DDVT; PDVT, proximal DVT; PE, pulmonary embolism; SD, standard deviation; VTE, venous thromboembolism.
Notes: Values in square brackets are 95% confidence intervals. Bold font indicates 95% confidence intervals which had no overlap between group A and either group B or group C or both; Y indicates no overlap with one other group; YY indicates no overlap with two other groups.
No iliac vein or proximal lower limb DVT, and no PE.
Iliac vein or proximal lower limb DVT (popliteal vein and above), but no PE.
Missing sex data for one patient in group C.
Includes 18 patients with multiple answers, four who were American Indian or Alaskan Native, and four who were Native Hawaiian or other Pacific Islander.
Missing CrCl data for 436 patients in group A, 801 in group B, and 554 in group C.
Missing BMI data for 213 patients in group A, 488 in group B, and 557 in group C.
Missing weight data for 155 patients in group A, 338 in group B, and 377 in group C.
Missing height data for 210 patients in group A, 482 in group B, and 546 in group C.
Missing smoking status data for one patient in group C.
Missing insurance status data for 318 patients in group A, 718 in group B, and 995 in group C.
Patients could have more than one employment status.