Table 3.
Accuracy of sonographic axillary staging for prediction of LAD (defined as presence of one or two metastatic lymph nodes on final pathology) according to number of suspicious lymph nodes on preoperative ultrasound in patients undergoing ALND (group 1: 1 suspicious lymph node on preoperative sonography/histology ≤ 2 two metastatic lymph nodes; group 2: 2 suspicious lymph nodes on preoperative sonography/histology ≤ 2 metastatic lymph nodes): whole cohort and patients ≥ 70 years
| Group 1 Sonography (1 lymph node)/ histology (≤ 2 lymph nodes) |
Group 2 Sonography (2 lymph nodes)/ histology (≤ 2 lymph nodes) |
|
|---|---|---|
| Percentages (95% CI) | ||
| Whole cohort | ||
| Accuracy | 94% (91–96%) | 89% (85–93%) |
| Sensitivity | 92% (87–95%) | 89% (84–93%) |
| Specificity | 96% (92–98%) | 89% (79–96%) |
| Positive predictive value | 96% (92–98%) | 96% (92–98%) |
| Negative predictive value | 92% (87–95%) | 73% (62–83%) |
| False-negative rate | 8% (5–13%) | 11% (7–16%) |
| False-positive rate | 5% (2–8%) | 11% (4–21%) |
| Age ≥ 70 years | ||
| Accuracy | 93% (88–97%) | 88% (81–93%) |
| Sensitivity | 94% (86–98%) | 90% (82–95%) |
| Specificity | 93% (85–98%) | 80% (59–93%) |
| Positive predictive value | 95% (88–98%) | 95% (88–98%) |
| Negative predictive value | 92% (83–97%) | 67% (57–83%) |
| False-negative rate | 7% (2–14%) | 10% (5–18%) |
| False-positive rate | 7% (2–16%) | 20% (7–41%) |