Table 5.

Associations between Salt Intake and Glaucoma-Related Outcomes in Participants with Antihypertensive Use and Diastolic Blood Pressure (DBP) <90mmHg and ≥90mmHg Antihypertensive Use in the Thessaloniki Eye Study Incidence Phase (n=1,076)

Participants with Antihypertensive Use and DBP <90mmHg (n=735)
Level of Overall Salt Intake and Prevalent Glaucoma Outcome	Unadjusted Odds Ratio (95% Confidence Interval); p-value	Partially Adjusted Odds Ratio (95% Confidence Interval); p-valuea	Fully Adjusted Odds Ratio (95% Confidence Interval); p-valueb
Any Open Angle Glaucoma (n=735)
Occasional Salt vs. Never	1.36 (0.71, 2.62); 0.35	1.37 (0.71, 2.64); 0.35	1.27 (0.61, 2.67); 0.52
Often Salt vs. Never	2.30 (1.06, 5.02); 0.04	2.34 (1.07, 5.12); 0.03	2.42 (1.00, 5.84); 0.05
Primary Open Angle Glaucoma (n=543)
Occasional Salt vs. Never	1.16 (0.48, 2.83); 0.74	1.17 (0.48, 2.85); 0.73	1.16 (0.41, 3.24); 0.78
Often Salt vs. Never	2.39 (0.89, 6.42); 0.08	2.47 (0.91, 6.69); 0.08	3.01 (0.95, 9.53); 0.06
Pseudoexfoliation Syndrome (n=704)
Occasional Salt vs. Never	1.41 (0.97, 2.05); 0.07	1.45 (0.99, 2.11); 0.05	1.31 (0.89, 1.95); 0.17
Often Salt vs. Never	0.77 (0.43, 1.37); 0.38	0.80 (0.45, 1.44); 0.46	0.71 (0.39, 1.29); 0.27
Participants with Antihypertensive Use and DBP ≥90mmHg (n=49)
Level of Overall Salt Intake and Prevalent Glaucoma Outcome	Unadjusted Odds Ratio (95% Confidence Interval); p-value	Partially Adjusted Odds Ratio (95% Confidence Interval); p-valuea	Fully Adjusted Odds Ratio (95% Confidence Interval); p-valueb
Any Open Angle Glaucoma (n=49)
Occasional Salt vs. Never	--	--	--
Often Salt vs. Never	--	--	--
Primary Open Angle Glaucoma (n=35)
Occasional Salt vs. Never	--	--	--
Often Salt vs. Never	--	--	--
Pseudoexfoliation Syndrome (n=47)
Occasional Salt vs. Never	1.43 (0.32, 6.45); 0.64	1.51 (0.30, 7.44); 0.62	1.93 (0.22, 16.11); 0.54
Often Salt vs. Never	3.33 (0.32, 34.82); 0.31	3.92 (0.35, 43.69); 0.27	19.81 (0.73, 538.17); 0.08

^aAdjusted for age, gender, and marital status

^bAdjusted for age, gender, marital status, cardiovascular disease, migraine, diabetes, history of cataract surgery, steroid use, active smoking status, systolic blood pressure, diastolic blood pressure, intraocular pressure, and central corneal thickness