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. 2022 Jun 30;12:11047. doi: 10.1038/s41598-022-14944-x

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© The Author(s) 2022, corrected publication 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Representative histological photomicrographs of selected organs of rats that orally received either the vehicle (0.5% methylcellulose) or the high dose (1000 mg/kg/day) of WSWPE for a total duration of 28 consecutive days, in this non-clinical safety study. Tissue sections have been stained with Haematoxylin and Eosin. Adrenal gland (× 40); Trachea, Urinary Bladder, Uterus (× 100); Pituitary, Pancreas, Thyroid, Seminal Vesicle, Prostate, Mammary Gland (× 400).