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. 2022 Mar 7;39(7):1363–1392. doi: 10.1007/s11095-022-03193-2

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 10 — Molecular structures of LAT1-binders differentiated from LAT1-substrates according to their half-maximal uptake time (T_½) studied at 10 μM concentration with LAT1-overexpressing MCF-7 human breast cancer cells. Additionally, ketoprofen compounds (in the middle) have also been provided with the Michaelis-Menten kinetic values (K_m and V_max).