Extended Data Fig. 14. MCMV and LCMV are cleared independent of caspase-6 and caspase-7.
a-b, Mice were infected IP with 5×104 pfu of MCMV. Viral titer in the liver was determined 4 days post infection from (a) n=6 WT, n=9 Casp7−/−, n=8 Prf1−/−; (b) n=10 WT, n=11 Casp6−/−, n=11 Prf1−/−. c-d, Mice were infected IP with 2×105 pfu of LCMV. Viral titer in the liver was determined by plaque assay 8 days post infection from (c) n=5 WT, n=6 Casp7−/−, n=6 Prf1−/−; (d) n=8 WT, n=9 Casp6−/−, n=5 Prf1−/−. All data are pooled from 2 experiments. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 (Two-sided Mann-Whitney U test). Bars indicate median values. Exact p and n values in Source Data EDF14.