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. 2022 Jun 30;13:3776. doi: 10.1038/s41467-022-31455-5

Table 1.

Characteristics of phages included in three cocktails used for treatment of a disseminated A. baumannii infection.

Phage cocktail Phage name Source Propagation host Morphology Accession # Genome size (bp) ICTV taxonomic subfamily and genus Closest classified relative in genus (nucleotide identity)
ΦPC (via intracavitary route) Maestroa CPT TAMU TP1 Myophage MT949699 169,176 Twarogvirinae, Hadassahvirus AbTZA1 (NC_049445), 91.4%
AC4 Ampliphi Biosciences TP1 Myophage OL770262 168,186 Twarogvirinae, Lazarusvirus vB_ApiM_fHyAci03 (NC_049438), 93.7%
ΦIV (via intravenous route) AB-Navy1 NMRC TP1 Myophage OL770258 166,113 Twarogvirinae, Lazarusvirus AM101 (NC_049511), 94.9%
AB-Navy4 NMRC TP1 Myophage OL770259 166,964 Twarogvirinae, Lazarusvirus vB_ApiM_fHyAci03 (NC_049438); 94.8%
AB-Navy71b DSMZ TP1 Myophage OL770260 166,382 Twarogvirinae, Hadassahvirus phage AbTZA1 (NC_049445); 96.5%
AB-Navy97c NMRC TP1 Myophage OL770261 165,480 Twarogvirinae, Lazarusvirus AM101 (NC_049511); 95.8%
ΦIVB (via intravenous route) AB-Navy97c NMRC TP1 Myophage OL770261 165,480 Twarogvirinae, Lazarusvirus AM101 (NC_049511); 95.8%
AbTP3phi1 NMRC TP3 Podophage OL770263 42,093 Beijerinckvirinae, Friunavirus vB_AbaP_B09_Aci08 (NC_048081), 84.0%

CPT TAMU Center for Phage Technology, Texas A&M University, NMRC Naval Medical Research Center, DSMZ Leibniz Institute DSMZ.

aMaestro is the representative of the three identical phages, C1P12, C2P21, and C2P24.

bAB-Navy71 was purchased from DSMZ under the name vB-GEC_Ab-M-G7.

cAB-Navy97 was used in both ΦIV and ΦIVB cocktails.