Table 1.
Characteristics of included studies.
Study | Region | Study design | Sample size | mAbs |
No mAbs |
Patients included | Transplant recipients | Usage of mAbs | ||
---|---|---|---|---|---|---|---|---|---|---|
Agea | Male (%) | Agea | Male (%) | |||||||
Ahearn2 2021 | USA | Retrospective | 181 | 49.3 ± 14.3 | 22(65) | 54 ± 14.5 | 83(56) | Outpatients | 94 kidney, 87 liver | Bamlanivimab or Casirivimab-imdevimab |
Bello3 2021 | France | Retrospective | 48 | 54 ± 14 | 10 | 59 ± 13 | 20 | Hospitalized, having symptoms for <6 d, and not requiring oxygen | 37 kidney, 2 liver, 5 heart, 2 kidney-pancreas, 1 kidney-liver | Bamlanivimab, bamlanivimab-etesevimab, casirivimab-imdevimab |
Chavarot4 2022 | France | Retrospective | 125 | 54 (46–62) | 21 (84.0) | 53 (37.8–52) | 54 (54.0) | Outpatient mild-to-moderate Omicron COVID-19 | 125 kidney | Sotrovimab |
Gueguen5 2022 | France | Retrospective | 235 | 57 (46–64.5) | 45 (56.3) | 57 (44–65) | 90 (58) | Recent symptoms (<5 days) and no need of oxygen | 155 kidney | Bamlanivimab, bamlanivimab-etesevimab, casirivimab-imdevimab |
Klein6 2021 | USA | Retrospective | 95 | 55.0 (31–79) | 15 (75.0) | 58 (38–78) | 45 (60.0) | (1) were not hospitalized due to COVID-19, (2) did not require oxygen therapy due to COVID-19, and (3) had symptoms for <10 days | 75 kidney | Bamlanivimab, bamlanivimab-etesevimab, casirivimab-imdevimab |
Sarrell7 2021 | USA | Retrospective | 165 | 55.1 (42.8–63.5) | 56 (60.2) | 52.0 (41.7–66.3) | 39 (54.2) | Outpatient mild to moderate COVID-19 | 50 kidney, 17 liver, 11 lung, 9 heart, 6 dual-organ | Bamlanivimab, casirivimab-imdevimab |
Tagaya8 2022 | Japan | Retrospective | 41 | 53.72 (26–73) | 13(72) | 48.04 (20–80) | 19 (82.6) | Hospitalized mild-to-moderate COVID-19 | 36 kidney, 3 liver, 2 bone marrow | Casirivimab-imdevimab |
Wang9 2022 | USA | Retrospective | 40 | 52 (37–61) | 15(56) | 44 (32–54) | 4(31) | Outpatient mild to moderate COVID-19 | 40 kidney | Bamlanivimab, casirivimab-imdevimab |
Age data presented as median (IQR) or mean (SD).