TABLE 3.

Telomere length (TL), mtDNA copy number (MCN), and deletion rate (MDD) according to psychiatric condition, median [95%CI].

	Control population	Major depressive episode	Psychotic syndrome	Major depressive episode and psychotic syndrome
n	136	56	20	54
TL (kb/cell)	170.3 [160.8; 181.4]	149.4 [139.9; 164.9]	211.4 [147.9; 230.4]*	154.2 [129.9; 162.7]
MCN (c/cell)	438.5 [370.5; 497.1]	373.2 [280.8; 526.3]	278.8 [234.1; 506.4]	415.8 [321.4; 549.1]
MDD (%)	0.72 [0.64; 0.80]	0.71 [0.65; 0.78]	0.55 [0.47; 0.69]	0.77 [0.69; 0.89]

MCN, mitochondrial copy number; MDD, mitochondrial DNA deletion; TL, telomere length; and CI, confidence interval. Tested vs. control population (Wilcoxon signed-post hoc rank test for age-adjusted LSM); *p < 0.05. LSM, least square mean.