TABLE 4.

Telomere length according to the multiplicity of the MDE, median [95%CI].

Multiplicity of episode	0 (control population)	1 episode	At least 2 episodes
n	136	71	39
TL (kb/cell)	170.3 [160.8; 181.4]	160.1 [151.1; 169.1]	129.9 [115.4; 144.4]*
MCN (cp/cell)	438.5 [372.9; 504.0]	404.8 [325.5; 484.0]	381.1 [236.5; 525.6]
MDD	0.72 [0.64; 0.79]	0.71 [0.63; 0.79]	0.79 [0.70; 0.88]

MCN, mitochondrial copy number; MDD, mitochondrial DNA deletion; TL, telomere length; and CI, confidence interval. Tested vs. control population (Wilcoxon signed-post hoc rank test for age-adjusted LSM); *p < 0.05. LSM, least square mean.