TABLE 6.
Determinants of “having a psychotic syndrome” among PWID.
|
Psychotic syndrome
|
||||||
| HCV positive (n = 161) |
HCV negative (n = 105) |
|||||
| Univariate |
Multivariate |
Univariate |
Multivariate |
|||
| OR | p-values | aOR [95%CI] | OR | p-values | aOR [95%CI] | |
| Telomere length (continuous) | 0.65 [0.46; 0.92] | 0.02 | 0.59 [0.39; 0.88] | 1.45 [0.98; 2.16] | 0.06 | 1.60 [1.01; 2.53] |
| Socio-demographic data: | ||||||
| Age (continuous) | 1.03 [0.98; 1.07] | 0.23 | 0.98 [0.93; 1.04] | 1.04 [0.99; 1.09] | 0.10 | 1.10 [1.03; 1.18] |
| Sex (ref : female) | ||||||
| Male and transgender | 0.79 [0.14; 4.48] | 0.79 | 0.39 [0.05; 2.77] | 2.17 [0.45; 10.4] | 0.30 | – |
| Drug consumption: | ||||||
| Heroin, frequency of consumption per month (ref: less than daily) | ||||||
| Daily | 0.75 [0.36; 1.56] | 0.45 | – | 1.35 [0.54; 3.37] | 0.52 | – |
| Methamphetamine, frequency of consumption per month (ref: < 4 times per month) | ||||||
| ≥4 times per month | 2.30 [1.05; 5.03] | 0.04 | – | 0.66 [0.22; 1.99] | 0.45 | – |
| Alcohol (ref: no excessive consumption) | ||||||
| Excessive consumption | 2.62 [1.22; 5.63] | 0.01 | 2.77 [1.37; 8.81] | 1.13 [0.46; 2.75] | 0.78 | – |
| Viral infections: | ||||||
| HIV (ref: HIV serology negative) | ||||||
| HIV serology positive | 0.55 [0.27; 1.10] | 0.09 | – | 3.18 [1.21; 8.36] | 0.02 | 4.42 [1.20; 16.27] |
| Treatments: | ||||||
| Methadone (ref: currently receiving methadone) | ||||||
| Not receiving methadone | 2.02 [0.98; 4.19] | 0.05 | 1.94 [0.83; 4.50] | 1.58 [0.63; 3.94] | 0.32 | – |
| ARV (ref: no) | ||||||
| Under ARV | 0.51 [0.24; 1.09] | 0.07 | – | 2.23 [0.76; 6.60] | 0.15 | – |
ref, non-syndrome; aOR, adjusted odd ratio; and CI, confidence interval.
Values in bold are statistically significant.