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. 2022 Jun 17;13:846844. doi: 10.3389/fpsyt.2022.846844

TABLE 6.

Determinants of “having a psychotic syndrome” among PWID.

Psychotic syndrome
HCV positive (n = 161)
HCV negative (n = 105)
Univariate
Multivariate
Univariate
Multivariate
OR p-values aOR [95%CI] OR p-values aOR [95%CI]
Telomere length (continuous) 0.65 [0.46; 0.92] 0.02 0.59 [0.39; 0.88] 1.45 [0.98; 2.16] 0.06 1.60 [1.01; 2.53]
Socio-demographic data:
Age (continuous) 1.03 [0.98; 1.07] 0.23 0.98 [0.93; 1.04] 1.04 [0.99; 1.09] 0.10 1.10 [1.03; 1.18]
Sex (ref : female)
Male and transgender 0.79 [0.14; 4.48] 0.79 0.39 [0.05; 2.77] 2.17 [0.45; 10.4] 0.30
Drug consumption:
Heroin, frequency of consumption per month (ref: less than daily)
Daily 0.75 [0.36; 1.56] 0.45 1.35 [0.54; 3.37] 0.52
Methamphetamine, frequency of consumption per month (ref: < 4 times per month)
≥4 times per month 2.30 [1.05; 5.03] 0.04 0.66 [0.22; 1.99] 0.45
Alcohol (ref: no excessive consumption)
Excessive consumption 2.62 [1.22; 5.63] 0.01 2.77 [1.37; 8.81] 1.13 [0.46; 2.75] 0.78
Viral infections:
HIV (ref: HIV serology negative)
HIV serology positive 0.55 [0.27; 1.10] 0.09 3.18 [1.21; 8.36] 0.02 4.42 [1.20; 16.27]
Treatments:
Methadone (ref: currently receiving methadone)
Not receiving methadone 2.02 [0.98; 4.19] 0.05 1.94 [0.83; 4.50] 1.58 [0.63; 3.94] 0.32
ARV (ref: no)
Under ARV 0.51 [0.24; 1.09] 0.07 2.23 [0.76; 6.60] 0.15

ref, non-syndrome; aOR, adjusted odd ratio; and CI, confidence interval.

Values in bold are statistically significant.