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. 2022 Jun 17;14:857521. doi: 10.3389/fnagi.2022.857521

Table 1.

Patinets baseline characteristics in training and validation cohorts.

Characteristics Training cohort
(n = 303)
Validation cohort
(n = 101)
P-value
Demographics
    Age (years) 57 (51, 64) 57 (51, 63) 0.903
    Gender (Female) 179 (59) 68 (67) 0.175
Medical history
    Hypertension 142 (47) 50 (50) 0.73
    Diabetes 9 (3) 3 (3) 1.000
    CHD 12 (4) 2 (2) 0.532
    Smoking 54 (18) 17 (17) 0.94
    Drinking 37 (12) 13 (13) 1.000
    Anticoagulant 11 (4) 3 (3) 1.000
Disease history 0.886
    ICH 3 (1) 0 (0)
    CI 6 (2) 1 (1)
WFNS grade 0.163
    I–II 227 (75) 68 (67)
    III 37 (12) 13 (13)
    IV 22 (7) 12 (12)
    V 17 (6) 8 (8)
Hunt and Hess grade 0.327
    I–II 211 (70) 59 (58)
    III 59 (19) 27 (27)
    IV 18 (6) 9 (9)
    V 15 (5) 6 (6)
Modified Fisher scale 0.037
    1–2 157 (52) 36 (35)
    3 76 (25) 37 (37)
    4 70 (23) 28 (28)
Aneurysm location 0.694
    ACA 273 (90) 93 (92)
    PCA 30 (10) 8 (8)
Aneurysm number 0.428
    Single 269 (89) 86 (85)
    Multiple (≥2) 34 (11) 15 (15)
Mean aneurysm size
    Neck (mm) 3.2 (2.4, 3.75) 3.5 (2.5, 4.3) 0.068
    Length (mm) 4.4 (3.15, 5.5) 4.9 (3.5, 6.7) 0.017
Aneurysm treatment 0.015
    Clipping 154 (51) 66 (65)
    Coiling 149 (49) 35 (35)
Decompressive craniectomy 16 (5) 11 (11) 0.084
Admission laboratory results
    Glucose (mmol/L) 6.96 (5.94, 8.17) 6.8 (5.61, 8.06) 0.396
    D-dimer (mg/L) 1.17 (0.58, 2.5) 1.36 (0.82, 2.5) 0.288
    WBC (109/L) 11.23
(9.27, 13.99)
11.21
(8.98, 14.4)
0.646
    Neutrophil (109/L) 9.57 (7.56, 12.28) 9.9 (7.27, 12.8) 0.887
    Lymphocyte (109/L) 0.9 (0.68, 1.25) 0.92 (0.65, 1.27) 0.842
    Monocytes (109/L) 0.5 (0.34, 0.7) 0.5 (0.33, 0.7) 0.655
Admission CT value (HU)
    ClotCT 57 (52, 62.02) 58 (54, 63) 0.17
    EdemaCT 26.82
(24.2, 28.98)
26.88
(25.07, 29)
0.36
DCI 85 (28) 27 (27) 0.898

DCI, indicates delayed cerebral ischemia; ACA, aneurysm includes anterior cerebral artery, middle cerebral artery, internal cerebral artery, anterior communicating artery; posterior communicating artery; PCA, aneurysm includes posterior cerebral artery, basilar artery, anterior inferior cerebellar artery, posterior inferior cerebellar artery, vertebral artery; ACA, anterior circulation aneurysm; PCA, posterior circulation aneurysm; WBC, White blood cell; CT, computer tomography; HU, Hounsfield Unit; WFNS, World Federation of Neurosurgical Surgeons; ICH, Intracerebral hemorrhage; CI, cerebral infarction; CHD, Coronary heart disease.