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. 2022 Jun 17;12:914247. doi: 10.3389/fcimb.2022.914247

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Copyright © 2022 Yang, Yang, Zhao, Wang, Li, Jin, Liu, Zhang, Zhang, Zhao, Liao, Li, Hua, Gu, Wang and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fecal microbiome variations and composition in BA and HC groups. (A) Overview of the study design. (B) Beta diversity (principal coordinates analysis based on the Bray-Curtis distance of genus abundance) between the two groups. (C) Microbiota with significantly different abundances between the two groups at the genus level (*p < 0.05, **p < 0.01, and ***p < 0.001). (D) Bar diagram of the fecal microbial composition in the two groups. (E) Community heatmap presenting information on the genus-level composition and abundance of the community between the two groups, with color changes reflecting the similarities and differences in community composition. BA, biliary atresia; HC, health control; PCoA, principal coordinated analysis.