Table 1.
Clinical characteristics of the BA and HC patients.
| Clinical characteristics | BA (n = 46) | HC (n = 38) | p-value |
|---|---|---|---|
| Female, n (%) | 22 (47.8) | 24 (63.2) | 0.273 |
| Age, days, median (IQR, Q1-Q3) | 55.0 (40.8-75.0) | 58.0 (46.5-115.5) | 0.100 |
| AST, U/L, median (IQR, Q1-Q3) | 242.5 (137.4-338.0) | 43.2 (37.1-67.9) | < 0.001 |
| ALT, U/L, median (IQR, Q1-Q3) | 131.0 (75.0-237.3) | 24.6 (19.2-41.1) | < 0.001 |
| GGT, U/L, median (IQR, Q1-Q3) | 336.5 (185.3-723.1) | 35.9 (18.1-103.6) | 0.001 |
| TBIL, μmol/L, median (IQR, Q1-Q3) | 168.1 (131.0-202.2) | 22.3 (9.9-71.0) | < 0.001 |
| DBIL, μmol/L, median (IQR, Q1-Q3) | 114.5 (83.1-146.1) | 4.1 (1.9-13.8) | < 0.001 |
| IBIL, μmol/L, median (IQR, Q1-Q3) | 49.6 (42.3-67.2) | 17.8 (7.8-34.1) | < 0.001 |
| TBA, μmol/L, median (IQR, Q1-Q3) | 114.3 (90.8-150.3) | 7.1 (3.5-11.9) | < 0.001 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BA, biliary atresia; DBIL, direct bilirubin; GGT, gamma-glutaryl transferase; HC, health control; IBIL, indirect bilirubin; TBA, total bile acid; TBIL, total bilirubin.