Table II.

Alterations in promoter methylation leading to the upregulated expression of various genes in uterine leiomyoma.

Upregulated gene*	Gene function	Fibroid sample type	Source
COL4A111	Collagen IV biosynthesis	Tissue (n = 10 Japanese)	(Maekawa et al., 2013)
COL4A212	Collagen IV biosynthesis	Tissue (n = 10 Japanese)	(Maekawa et al., 2013)
COL6A313	Collagen VI biosynthesis	Tissue (n = 10 Japanese)	(Maekawa et al., 2013)

*Genes which are upregulated and have hypomethylation at their promoter in uterine leiomyoma along with their gene function and fibroid sample type used in the respective studies are summarized.

¹¹collagen type IV alpha 1 chain

¹²collagen type IV alpha 2 chain

¹³collagen type VI alpha 3 chain