Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 17;13:926099. doi: 10.3389/fmicb.2022.926099

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Li, Li, Guo, Wen, Meng and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Structure complex of EcPsuK with m1Ψ. (A) Structure superposition of EcPsuK-m1Ψ and EcPsuK-Ψ. m1Ψ is colored in green, and Ψ is colored in yellow. The lost regions in the EcPsuK-Ψ complex are indicated by black arrows. (B) Binding site of a monovalent ion. The 2| Fo| –| Fc| σ-weighted map is contoured at 1.5σ. K⁺ is colored purple shown as a sphere. (C) Detailed interactions between EcPsuK and m1Ψ. EcPsuK is shown as cartoon and colored in yellow, the residues in contact with Ψ are shown as sticks, and m1Ψ is shown as stick colored in green. The hydrogen bonds are shown as black dashed lines. The red sphere represents the water molecule. The 2| Fo| –| Fc| σ-weighted map is contoured at 1.5σ. (D) Substrate specificity of EcPsuK for pseudouridine and other nucleoside analogs. n.d., not detected.