Figure 4.
Silencing of AKIP1 enhances Ishikawa cell chemosensitivity. Effect of AKIP1 siRNA on relative cell viability under different concentrations of (A) cisplatin and (B) paclitaxel treatment in Ishikawa cells (AKIP1 siRNA group vs. NC siRNA group). Comparison of IC50 value of (C) cisplatin and (D) paclitaxel in Ishikawa cells transfected with NC siRNA and AKIP siRNA (data are presented as mean ± SD). AKIP1, A-kinase-interacting protein 1; NC, negative control; siRNA, small interfering RNA; IC50, half maximal inhibitory concentration; SD, standard deviation.
