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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Angew Chem Int Ed Engl. 2021 May 14;60(25):14163–14170. doi: 10.1002/anie.202102453

Figure 3.

Figure 3.

Sequence analysis of the TSs found in Streptomyces sp. (CL12-4). (A) Phylogenetic analysis of the nine TSs found in the genome of CL12-4. Characterized TSs from Streptomyces are labeled with their UniProt accession numbers. Colored labels (shown in legend) indicate the type of terpene synthase. Structures discussed in the text are shown with their associated TSs. Bootstrap values >50% (based on 1000 resampled trials) are given at nodes. (B) Sequence similarity network of TSs from Streptomyceae at an e-value threshold of 10−60. Clusters of TSs are colored corresponding to the legend in (A) and based on the characterized TSs found within. The eight homologous TSs from actinobacteria were included to highlight their similarity to Bnd4.