Table 3.
Prediction of evolutionary conservation by ConSurf
| SNP ID | Amino acid change | Prediction (Score) | ConSurf Prediction | Functional/structural |
|---|---|---|---|---|
| rs1800973 | T88N | 3 | Variable | - |
| rs121913547 | I74T | 8 | Conserved | - |
| rs121913549 | F75I | 9 | Conserved | s |
| rs387906535 | D67H | 6 | Moderately conserved | - |
| rs387906536 | W82R | 9 | Conserved | f |
| rs121913548 | D85H | 5 | Moderately conserved | - |
| rs147465274 | R80C | 4 | Moderately conserved | - |
| rs200491782 | R116S | 4 | Moderately conserved | - |
According to the ConSurf server, “f” — functional residue and “s” — structural residue