Skip to main content
. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Refract Surg. 2017 Dec 1;33(12):834–839. doi: 10.3928/1081597X-20170921-02

Figure C.

Figure C.

Effect of suberoylanilide hydroxamic acid (SAHA) and mitomycin C (MMC) on keratocyte number and density. Representative DAPI nuclear staining showing keratocyte population and density at 1 and 4 months in rabbit corneas treated with balanced salt solution (control), SAHA (25 μM), and MMC (0.02%) after photorefractive keratectomy (PRK). Control (A and C) or SAHA (B and D) treatment did not decrease keratocyte number and density in the stroma, whereas MMC treatment (C and F) caused significant keratocyte depletion of keratocyte number and density, especially in the anterior stroma as indicated by the arrows (C and F) at 1 and 4 months. Scale bar = 100 μm (Blue = DAPI-stained nuclei)