FIG 5.

Cells present in the liver and spleen of naive mice and mice with established HAV infection following miglustat or sham treatment as shown in Fig. 4A. (A) Total number of leukocytes present in the liver. (B) Cell types present in the liver. cDC, conventional dendritic cells. (C) Proportions of intrahepatic CD4⁺ and CD8⁺ lymphocytes staining positively for the activation marker CD44. (D) Total number of leukocytes in the spleen. (E) Cell types present in the spleen. (F) Proportions of CD4⁺ and CD8⁺ lymphocytes in splenic tissue staining positively for the activation marker CD44 (n = 4 in each group). P values are shown only for significant pairwise differences from untreated, infected mice, determined by 2-way ANOVA with Šidák’s multiple-comparison test (*, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001).