Table 3.
Adjusted cox regression hazard ratios for melanoma-specific survival of each stage of the 7th and 8th edition TNM melanoma staging system
| TNM7 | TNM8 | |||||
|---|---|---|---|---|---|---|
| Hazard Ratio | 95% CI | P-value | Hazard Ratio | 95% CI | P-value | |
| Stage | ||||||
| IA | 0.03 | (0.02–0.05) | < 0.001 | 0.04 | (0.02–0.06) | < 0.001 |
| IB | 0.12 | (0.08–0.18) | < 0.001 | 0.17 | (0.11–0.26) | < 0.001 |
| IIA | 0.35 | (0.24–0.51) | < 0.001 | 0.33 | (0.22–0.48) | < 0.001 |
| IIB | 0.66 | (0.47–0.93) | 0.019 | 0.66 | (0.46–0.93) | 0.017 |
| IIC | Reference | - | - | Reference | - | - |
| IIIA | 0.56 | (0.35–0.91) | 0.020 | 0.28 | (0.14–0.56) | < 0.001 |
| IIIB | 0.94 | (0.65–1.35) | NS | 0.86 | (0.54–1.36) | NS |
| IIIC | 1.95 | (1.35–2.82) | < 0.001 | 1.42 | (1.02–1.97) | 0.040 |
| IIID | - | - | - | 4.14 | (2.26–7.58) | < 0.001 |
| IV | 6.48 | (4.04–10.37) | < 0.001 | 6.57 | (4.08–10.57) | < 0.001 |
Adjusted for report/diagnostic year, age, sex, Elixhauser comorbidity index, neighbourhood income quintiles, place of residence, residential area, histological subtype, location, adjuvant/palliative systemic therapy and adjuvant/palliative radiotherapy