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. 2022 Mar 4;31:100853. doi: 10.1016/j.ymgmr.2022.100853

Table 3a.

Number of PDE-ALDH7A1 adults with clinically relevant deviant scores on PROMIS item banks with range normal to severe.

PROMIS Within normal limits Mild Moderate Severe
Anxiety 6 (60%) 1 (10%) 3 (30%)
Depression 9 (90%) 1 (10%)
Anger 8 (80%) 2 (20%)
Physical functioning 5 (50%) 2 (20%) 2 (20%) 1 (10%)
Ability participate 5 (50%) 2 (20%) 3 (30%)
Cognitive functioning 2 (20%) 1 (10%) 6 (60%) 1 (10%)
Cognitive abilities 4 (40%) 2 (20%) 4 (40%)

Mild = ± 0.5–1.0 SD from the mean, moderate = ± 1.0 to 2.0 SD from the mean, severe = ± more than 2.0 SD from the mean.